pentobarbital will decrease the extent or influence of lopinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.Keep track of Intently (2)pentobarbital will minimize the level or impact of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Strong CYP3A4 inducers could lessen suvore